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Disadvantages of the complement fixation test

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Step-by-step explanation:

The complement fixation test has several disadvantages.

First, the test is time-consuming and labor-intensive. It requires multiple steps and a long incubation period, making it difficult to use for rapid diagnosis.

Second, the sensitivity of the test is relatively low compared to other tests. This means that it may miss some cases of infection.

Third, the test is prone to false positive results due to the presence of non-specific antibodies in the sample. This can lead to incorrect diagnosis.

Fourth, the test is not as specific as other tests, which means it may produce false positive results due to cross-reactivity with other antigens.

Finally, the test is expensive and requires specialized equipment and reagents. This makes it difficult to use in resource-limited settings.

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