Answer:When CODIS (Combined DNA Index System) is attempting to match DNA samples to DNA profiles in its database, it is attempting to match 13 different regions in the nuclear DNA (Option B). These regions, also known as loci, contain genetic markers that are unique to an individual, and by matching the markers at these loci between a sample and a profile in the database, CODIS can determine if there is a match between the two. The use of multiple loci helps to increase the accuracy and reliability of DNA matches, as the chance of two individuals having the same DNA profile at all 13 loci is very low.
Step-by-step explanation:
When CODIS (Combined DNA Index System) is attempting to match DNA samples to DNA profiles in its database, it is attempting to match 13 different regions in the nuclear DNA (Option B). These regions, also known as loci, contain genetic markers that are unique to an individual, and by matching the markers at these loci between a sample and a profile in the database, CODIS can determine if there is a match between the two. The use of multiple loci helps to increase the accuracy and reliability of DNA matches, as the chance of two individuals having the same DNA profile at all 13 loci is very low.