Question

Sickle-cell anemia is caused when a mutation results in the replacement of glutamate with valine. Which type of mutation is observed here?

a.chromosomal mutation
b.frameshift mutation
c.substitution mutation

Answer 1

C.) Substitution or Silent mutation

Answer 2

The type of mutation which is observed here is substitution mutation. According to the fact that sickle cell anaemia is occuring at the at beta-globin gene, the correct answer is c.substitution mutation as it shows mutation point as a single base. Hope it will help! Regards.