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What system does Addison disease affect

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The adrenal glands, your adrenal glands are just above your kidney, they produce hormones that effect how your body will react to stress. In people with Addison's, the adrenal glands do not produce enough corticosteroid hormones, such as cortisol and  aldosterone.
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The adrenal glands are part of the endocrine system. ... The adrenal glands are located just above your kidneys. They produce hormones that affect how your body responds to stress. In people who have Addison's disease, the adrenal glands do not produce enough corticosteroid hormones, such as cortisol and aldosterone.

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