Answer:
Its swampy location had a lot of disease.
Step-by-step explanation:
Back in 1609-10, more than eighty percent of the people who were in Jamestown died from either disease or starvation. The survivors abandoned the area, although they ended up going back after they found, in the James River, a convoy with supplies. Jamestown was swampy and isolated. Mosquitoes were a plague. It was complicated to get in and out and had little space, which helped a lot for the diseases to spread out.