We would be using the time formula which is distance over speed.
 Distance between 2 airports= 2400 miles 
 Average speed of airplane= 450 mph 
 Flight time = 2400/450 = 5.3 hrs = 315 minutes = 5 hours and 18 minutes
 But there is a 35 minutes bus ride, so therefore 5 hours and 18 mins + 35 mins = 5 hours and 53 mins.