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Patients with alzheimer's disease tend to have abnormally ______ levels of acetylcholine and abnormally ______ levels of glutamate.

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User JohnWolf
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The binding of acetylcholine to ACH receptors results in the change on membrane of the target cell. Acetylcholine is rapidly removed by enzymatic breakdown.As the brain cells of an Alzheimer patient dies, excess amount of glutamate is released.So patients with Alzheimer's disease tend to have abnormally depleted levels of acetylcholine and abnormally higher levels of glutamate.
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User Lbolla
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