Step-by-step explanation:
Elements present in group 18 are known as noble gases. The outermost shell of these elements are completely filled.
Hence, they have low reactivity towards any kind of chemical reaction.
Elements of noble gas family are helium, neon, argon, krypton, xenon, and radon.
Thus, we can conclude that family of noble gases in the periodic table is least likely to enter into chemical reactions.