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After the fall of the Byzantine Empire, the Ottomans took control of the only spice trade route that existed at that time. Europeans began to search for a sea route around what

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User Gianmt
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They searched for a route around Africa. One example of this would be De Gama, who sailed around the Cape of Good Hope for the Portugese, into the Indian Ocean World, where they established trading firms. 
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User John Hinnegan
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Answer:

Cape of good Hope

Step-by-step explanation:

I just took the test in K12

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User Mumbles
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