asked 152k views
0 votes
How are mutations prevented during dna replication?

2 Answers

2 votes

Answer:

By proofreading activity of DNA polymerase.

Step-by-step explanation:

Mutations are defined as permanent, inherited changes in the nucleotide sequence of genetic material. Mutations can be caused by errors during the DNA replication, when the enzyme DNA polymerase adds a wrong nucleotide to the growing DNA strand.

When a wrong nucleotide or base is detected (by proof-reading activity of DNA polymerase) in the growing chain, DNA replications halts and the incorrect base is removed by the enzyme's exonuclease activity. Then, DNA polymerase again starts to replicate the DNA, using its polymerizing activity.

Thus, the errors can be prevented during DNA replication by DNA polymerase as it shows both polymerizing, exonuclease and as well as proof-reading activity.

answered
User Mimiz
by
8.9k points
5 votes
DNA polymerase checks DNA for errors. DNA polymerase checks DNA for errors by breaking the hydrogen bonds between the paired nitrogen bases in the DNA molecule. This causes the molecule to separate into two individual strands.
answered
User Gojko Adzic
by
8.1k points

No related questions found

Welcome to Qamnty — a place to ask, share, and grow together. Join our community and get real answers from real people.