Question

Which is the best way to describe the fit between
an enzyme and its substrate?

Answer 1

The induced fit model best describes the dynamic and flexible interaction between an enzyme and its substrate, where the enzyme adjusts its shape for optimal fit.

Step-by-step explanation:

The best way to describe the fit between an enzyme and its substrate is through the induced fit model. This model suggests that enzymes are not rigid structures; rather they are flexible and can adjust their shape in response to interaction with a substrate. The induced fit model compares enzyme-substrate interaction to a hug between two people, where the enzyme slightly changes its structure to achieve the best possible fit with the substrate's transition state, much like a rubber glove that molds to the shape of a hand inserted into it. This flexibility ensures a high degree of specificity while also allowing for minor adjustments to optimize interactions with different, yet structurally related substrates.

Answer 2

when i studied biology, the analogy was a lock and key since certain keys only work with certain locks, like certain enzymes only work with certain substrates.