6. What do you think is the underlying cause of all these symptoms in Barbara?
What is wrong with her?
7. Some patients with thyroid or thyroid hormone problems develop a goiter. List
two possible causes of this goiter.
8. Barbara does not have a goiter at the moment. If her condition continues unchecked will
she develop one?
9. Extrapolate the knowledge you have of the hypothalamic-anterior pituitary-thyroid
negative feedback loop to explain how an anabolic steroid (testosterone) abuse would
lead to testicular atrophy (breakdown).