Geography is a very important part of choosing where you would like to settle. There are many components that factor into everyday life that are very important, like agriculture, food, and climate.
The climate is different in different parts of the world. For example, if you prefer cold climates you would settle up North, but if you were to prefer hotter climates you would most likely settle in the South. The climate also changes the soil and farming.
Due to the warmer climate, soil in the South is richer and better for agricultural purposes. This was why the South was more focused on farming and agriculture, while the North got their income from industrialization.
Different animals and plants are in different regions as well. Different species of animals will reside in different areas and different plants may prefer certain climates.
If you are planning on farming, you will prefer very large flat plains. If you plan to live in the mountains you may live somewhere bumpy and rocky.