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What challenges did the Spanish face as they traveled to the New World?

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Answer:

As Europeans and African slaves began to arrive in the New World, they brought with them the infectious diseases of Europe and Africa.

Rampant epidemic disease, to which the natives had no prior exposure or resistance, was one of the main causes of the massive population decline of the indigenous populations of the Americas.

Diseases like smallpox, typhus, measles, and influenza were responsible for the destruction of large segments of the Caribs, Arawaks, Beothuks, and Mesoamerican and other indigenous empires.

The scope of the epidemics over the years was tremendous, killing millions of people possibly in excess of 90% of the population in the hardest hit areas.

Step-by-step explanation:

answered
User Spotman
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Answer:

They had a big cold and alot of them died and was buried alive.

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User Oz Solomon
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