Question

A student is studying cotranslational import into the ER lumen in a cell-free system. What would be the expected result if the student were to replace all of the GTP in the system with a nonhydrolyzable analog of GTP

Answer 1

The SRP would remain bound to the SRP receptor on the ER surface.

Step-by-step explanation:

Because Signal recognition particle (SRP) receptorl, is a dimer composed of 2 different subunits that are associated only with the rough ER in human cells. It functions mainly is to identify the SRP units. And it SRP binds to a hydrophobic N-terminal signal sequence as it emerges from the ribosome.