Question

Which of the following cis-acting elements of focused promoters serves as the binding site for TFIID?

1. TATA Box
2. Enhancer
3. BRE
4. INR

Answer 1

1. TATA Box

Step-by-step explanation:

TFIID, also called transcription factor II D, is a Transcription Factor that interacts with the minor groove of the TATA box. The TATA element is a core promoter component present in genes of eukaryotic organisms, which is formed by the consensus sequence TATA(A/T)A(A/T).

TFIID is involved in the first stage of the transcription process, during the formation of the pre-initiation complex. TFIID contains a TATA-binding subunit and a complex of associated factors (TBP-associated factors) that interact with specific RNA polymerases, for example, by interacting with the RNA polymerase II (RNAP II) during transcription of the messenger RNA (mRNA).