Question

In eukaryotes, transcription factors and enhancer sequences are used to regulate transcription. Classify the statements as true or false. True False

Answer 1

True

Explanation:

Transcription Factors (TFs) are proteins that function to activate the transcription by binding to specific DNA sequences of genes named promoter regions, which are localized near to the transcription start site. Generally, TFs have well-characterized, evolutionarily conserved domains, thereby enabling their classification into different families.

Enhancers are short (50–1500 bp) DNA sequences localized upstream or downstream of the transcription start site, in a distance ranging from 1 to 100 kilobases. Enhancers function to activate the transcription by binding to specific proteins and by encoding RNA or by producing regulatory non-coding RNAs (ncRNAs). These sequences may activate the transcription both in cis (i.e., on the same chromosome) and in trans (i.e., on another chromosome).