Answer:
A total of 469 seats in the U.S. Congress (34 Senate seats and all 435 House seats) are up for election on November 8, 2022.
Below, you will find information on the partisan breakdown of each chamber, seats up for election, which seats changed party hands in the last election, and incumbents not seeking re-election.
Partisan breakdown
U.S. Senate
Democrats gained a net total of three seats in the 2020 Senate elections. This brought their caucus total to 50, including two independents who caucus with Democrats. Republicans held the other 50 seats following the elections.