Question

The synthesis of phosphatidylcholine has alternate pathways. In mammals, for example, phosphatidylcholine (PC) can be synthesized by two pathways: a pathway that begins with choline and a pathway that includes phosphatidylethanolamine. Classify each description as pertaining to PC synthesis from choline or from phosphatidylethanolamine.

Answer 1

Choline:

-predominate pathways in mammalian

-Pathway requires phosphorylation by CTP

-Pathway involves 1,2-diacylglycerol

Phosphatidylethanolamine:

-possible pathway in mamaliam liver

-pathway requires S-adenosylmethionine as the source of methyl groups.

-pathway involves a series of methylations