Denatured alcohol and isopropyl alcohol are as similar as they as different. They are both used for cleaning and harmful to people if ingested. But isopropyl seems to be more effective than denatured alcohol. Denatured alcohol has been found to be more toxic and can harm our skin. But when it comes to cleaning, denatured alcohol can be used, but should not be used over isopropyl as it can leave behind residue, especially when it comes to electronic devices. Isopropyl, especially 70%, is more effective because it has more water, which can help it dissolve more slowly, penetrate cells, and kill bacteria.