Question

atty acid synthesis begins with a preparatory step in which ___ is transferred from ___ to the ___. However, it cannot pass through the membrane, so it is transported as ___, which is cleaved to ___ to ___.

Answer 1

acetyl coA

mitochondria

cytoplasm

citrate

acetyl CoA

oxaloacetate

Step-by-step explanation:

The step by step fatty acid synthesis involve the following -

a) The first step is the carboxylation of cytosolic acetyl-CoA by by acetyl CoA carboxylase with in the cytosol or cytoplasm of the cell. The cytosolic acetyl-CoA is from pyruvate in mitochondria which are not permeable to acetyl CoA

b) Formation of multienzyme complex which link intermediates to acyl carrier protein.

c) NADPH is used to acetyl-CoA through series of condensation, reduction and dehydration reaction

d) Synthesis of malonyl-CoA

Hence, the correct options are

acetyl coA

mitochondria

cytoplasm

citrate

acetyl CoA

oxaloacetate