Question

Acetylcholine binds to a GPCR on heart muscle. The activated receptor stimulates a trimeric Gi protein, which opens a K channel in the plasma membrane. Following stimulation with Acetylcholine, what impact on heart rate would you expect from each of the following?

Answer 1

Generates a reduction in heart rate.

Step-by-step explanation:

These channels, initially called K (Ach), slow the pacemaker cell's depolarization and decrease the heart rate.