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Demyelination results from issues associated with myelin producing cells. What is an example of a myelin producing cell in the cns?

1 Answer

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CNS

Step-by-step explanation:

An example of a myelin producing cell in the CNS is oligodendrocyte

  • The major function of oligodendrocytes is the formation of myelin
  • Myelin acts as an insulator of axonal segments and is a prerequisite for the high velocity of nerve conduction
  • Larger axons form thicker myelin
  • During development, oligodendrocytes arise from precursors located in the sub-ventricular zone such as the sub-ventricular zone of the lateral ventricles for the cerebrum or the fourth ventricle for the cerebellum
  • In the spinal cord, oligodendrocytes originate from the ventral regions of the neural tube and in the optic nerve they migrate into the nerve from the third ventricle
  • It is the oligodendrocyte precursor cells which migrate to their destination where they then differentiate into the more mature oligodendrocytes
  • The proliferation of the oligodendrocyte progenitor cells is controlled by a number of growth factors released predominantly from neurons but also from astrocytes such as platelet derived growth factor (PDGF) or fibroblast growth factor (FGF)
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