Question

Which of the following mechanisms is used by gram-negative bacteria to cross the blood-brain barrier?

A) producing fimbriae
B) inducing endocytosis
C) producing toxins
D) inducing TNF
E) antigenic variation

Answer 1

Which of the following mechanisms is used by gram-negative bacteria to cross the blood-brain barrier? D) Inducing TNF

Step-by-step explanation:

The blood brain barrier is a barrier formed by brain microvascular endothelial cells, astrocytes and pericytes. Pathogens can cross this barrier by using different mechanisms. The Tumor Necrosis Factor (TNF) is the way gram-negative bacteria cross this mentioned blood-brain barrier.