Find the gradient:
m = y2-y1 / x2-x1
m = 6-(-4) / 0-1
m = 10 / -1
m = -10
Slope intercept form:
y = mx + c
Input the values from one of the points to find c (imputing (1,-4) to y=mx+c):
-4 = -10(1) + c
-4 = -10 + c
c = -4 + 10
c = 6
Therefore, the equation is:
y = -10x + 6