Question

The catalytic efficiency of many enzymes depends on pH. Chymotrypsin shows a maximum value of kcat/KM at pH 8. Detailed analysis shows that kcat increases rapidly between pH 6 and 7 and remains constant at higher pH. KM increases rapidly between pH 8 and 10. Suggest explanations for these observations.

Answer 1

The catalytic efficiency of the enzyme depends on several factors that can affect the activity of the enzymes. This factors include Temperature, pH, concentration of the substrate, concentration of enzyme and the presence of activators and inhibitors.

Step-by-step explanation:

The catalytic efficiency of the enzyme depends on several factors that can affect the activity of the enzymes. This factors include Temperature, pH, concentration of the substrate, concentration of enzyme and the presence of activators and inhibitors.

For instance, the pH is an essential factor that has to be maintained properly for the appropriate catalysis by an enzyme. The most favorable pH of most of enzymes present from 6 to 8.