Question

Considering the following hydropathy plot for a protein with 4 transmembrane domain. This protein functions in the plasma membrane. The position of 3 positively charged residues near the first transmembrane helix is indicated by an asterisk on the plot. 1. Are the protein termini expected to be located inside (I) or outside (O) of the cell or display one terminus on the inside and the other one on the outside (I/O)

Answer 1

Explanation:

Answer - O : 2

N-glycans to Asn-X-Ser/Thr sequence occurs on the lumenal side of the endoplasmic reticulum. So, it is present in outside of the cell.