Question

The discovery of what properties of neurotransmission caused neuroscientists to rethink Dale’s Principle?

Answer 1

3.co-release and cotransmission of more than one neurotransmitter

Step-by-step explanation:

The complete question is as follows:

The discovery of what properties of neurotransmission caused neuroscientists to rethink Dale's Principle?

1. inhibition of neural activity
2. neural communication at more than one place at a neuron
3. co-release and cotransmission of more than one neurotransmitter
4. finding similar neuronal activity in more than one location in the brain

• Dale's principle was given by a scientist named Henry Dale in 1940's and the principle state that each neuron is capable of releasing only a single type of neurotransmitter.
• This principle meant that a particular neuron is capable of performing only a single function at all the synapses.
• However, Dale's principle were soon proven to be false when it was discovered that there are many neurons capable of releasing more than one neurotransmitter at a time and this is termed as cotransmission and co-release of the neurotransmitters.
• An example of co-transmission is the release of GABA along with substance P as cotransmitter.