Answer:Non-covalent bonds
Step-by-step explanation:
The Non-covalent bonds are bonds such as van der Waals forces of attraction, the Hydrogen bonds, hydrophobic bonds and so on. The Non-covalent bonds are very important types of bonding in large biological molecules.
Just like the question says, the Non-covalent bonds, ''makes it possible for a macromolecule to interact with great specificity with just one out of the many thousands of different molecules present inside a cell".
Ionic bonding is also a Non-covalent bonding. They(Non-covalent bonds) helps in the stability of large macromolecules.