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What can be the problems encountered while using magnesium stearate as a lubricant with poorly soluble drug in hard gelatin capsules?

1 Answer

4 votes

Answer:

The answer is explained below:

Step-by-step explanation:

Magnesium stearate is primarily used as a lubricant and as anti-adherent and glidant. This occurs as plate-like crystals staked like a deck of cards.

The use of magnesium stearate causes compression and dissolution problems.

And because stearates are alkaline in reaction, it can not be used with some acidic drugs.

answered
User TJBlackman
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