asked 106k views
1 vote
What was the biochemical reason for the "Ox Phos War," i.e., why was Peter Mitchell's hypothesis considered heretical

asked
User Sirmabus
by
9.1k points

1 Answer

2 votes

Answer:

The options

A ) It was thought that all ATP in the cell was synthesized from the glycolytic pathway in the cytosol and that mitochondria are dispensable.

B) It was thought that oxidative phosphorylation required a reactant with a high energy bond (~X) and it was just a matter of who could find it first.

C) The reaction A~X + Pi + ADP. A + X + ATP was thought to be the preferred pathway using both a membrane potential and Na+ gradient.

D) Since Peter Mitchell was a wealthy scholar who lived in a mansion with a built-in laboratory, it was assumed he was eccentric and wrong.

The CORRECT ANSWER IS B

B) It was thought that oxidative phosphorylation required a reactant with a high energy bond (~X) and it was just a matter of who could find it first.

Step-by-step explanation:

Majority of the biochemists at that period were experimenting to evaluate for a high energy phosphorylated intermediate also known as ~X-P and they believed it is the answer to the question or experiment.

Peter Mitchell's hypothesis was considered heretical because it was independent on ~X-P. His model was considered unusual and a new model plus he had his own private laboratory... a factor wasn't common too at that period.

It was called "Ox Phos War due to the disagreement "war" as biochemists had to chose sides.

answered
User Pieter
by
8.6k points
Welcome to Qamnty — a place to ask, share, and grow together. Join our community and get real answers from real people.