Question

The production of ammonia in the reaction catalyzed by glutamate

dehydrogenase:
A. requires the participation of NADH or NADPH.
B. proceeds through a Schiff base intermediate.
C. may be reversed to consume ammonia if it is present in
excess.
D. is favored by high levels of ATP or GTE
E. would be inhibited when gluconeogenesis is active.

Answer 1

The correct answer is - option C.

Explanation:

Glutamate dehydrogenase is also known as GDH which present in most of the microorganisms or the mitochondria of eukaryotic organisms. It is the only enzyme that can use both NAD+ and NADP+.

Glutamate dehydrogenase is inhibited by the GTP or ATP. One of the main causes of the catabolism amino acid is metabolites for gluconeogenesis. If the gluconeogenesis is likely to be active due to the result of when glutamate dehydrogenase is active.

Thus, the correct answer is - option C.