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When did historians start seeing the explorers bring these epidemics (Ex. small pox) which destroyed populations and thereby creating wilderness?

When did historians start seeing the explorers bring these epidemics (Ex. small pox) which destroyed populations and thereby creating wilderness?
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When did historians start seeing the explorers bring these epidemics (Ex. small pox) which destroyed populations and thereby creating wilderness?

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User Headkit
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Early 15th century is when they started seeing explorers
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User Niels Keurentjes
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