Second-generation H1 antagonists cause less CNS depression because they are selective for peripheral H1 receptors and because of which other property?

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asked Aug 2, 2021 103k views

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Kevinnls · Answer 1 · 2021-08-07T10:01:53+0000

Answer:

THEIR INABILITY TO CROSS THE BLOOD-BRAIN BARRIER AT THERAPEUTIC LEVELS.

Step-by-step explanation:

Second-generation antihistamines (e.g., loratadine, terfenadine) lack the ability to pass through the blood-brain barrier at certain therapeutic levels.

Second-generation H1 antagonists cause less CNS depression because they are selective for peripheral H1 receptors and because of which other property?

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