Question

Which of the following statements is incorrect about hexokinase?

a. The reaction it catalyzes during glycolysis is reversible under intracellular conditions.
b. It catalyzes the first step of the glycolytic pathway.
c. It is a soluble, cytosolic protein.
d. Humans have four different hexokinase enzymes, all of which catalyze the same reaction.

Answer 1

a. The reaction it catalyzes during glycolysis is reversible under intracellular conditions.

Step-by-step explanation:

Hexokinase is an enzyme utilized in the phosphorylation of six carbon sugars during glycolysis or glycogen synthesis. The enzyme has the capacity to transfer phosphate group from ATP to six carbon sugar substrates.

Hexokinases are proteinous and there are four different types in human including hexokinase I, II, III, and IV.

Phosphorylation of hexoses by hexokinase under intracellular condition constitutes the first step of glycolytic pathway and it is irreversible.

The correct option is a.