How does the structure of insulin support its function? (How does it's shape determine what it does?)

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asked Dec 23, 2023 14.2k views

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Esben Von Buchwald · Answer 1 · 2023-12-29T21:30:15+0000

There are 3 conserved disulfide bridges which help keep the two chains together. Insulin can also form dimers in solution due to the hydrogen bonding between the B chains (shown as white lines). The dimers can further interact to form hexamers due to interaction between hydrophobic surfaces.

How does the structure of insulin support its function? (How does it's shape determine what it does?)

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