Question

Compare the shape of a normal red blood cell to that of a red blood cell in

someone with sickle cell anemia.

Answer 1

Red blood cells with normal hemoglobin are smooth, disk-shaped, and flexible, like doughnuts without holes. They can move through the blood vessels easily. Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent, like the letter C.