Why do nucleotides need to be activated before DNA synthesis?

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asked Feb 23, 2022 126k views

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Guillermo Ruffino · Answer 1 · 2022-02-28T08:32:34+0000

They always need a template. They can only add nucleotides to the 3' end of a DNA strand. They can't start making a DNA chain from scratch, but require a pre-existing chain or short stretch of nucleotides called a primer.

Why do nucleotides need to be activated before DNA synthesis?

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Why do nucleotides need to be activated before DNA synthesis?