Question

List at least 4 factors or agents which can cause damage to DNA.


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Answer 1

1. Ultraviolet radiation
2. X-ray
3. Oxidative stress
4. Alkylating agents (a type of anticancer drugs)

Answer 2

Metabolism releases compounds that damage DNA including reactive oxygen species,

reactive nitrogen species,

reactive carbonyl species,

lipid peroxidation products and alkylating agents