Question

Probes that bind under very stringent hybridization conditions resulting in the differential binding over one nucleotide are called ________. Probes that bind under very stringent hybridization conditions resulting in the differential binding over one nucleotide are called ________. short, variable repeats VNTRs microsatellites allele-specific oligonucleotides (ASOs) generation-specific probes

Answer 1

allele-specific oligonucleotides (ASOs)

Step-by-step explanation:

An allele-specific oligonucleotide (ASO) is a piece of synthetic DNA that is short and usually a complementary to the sequence of a target DNA, It is an oligonucleotide of 15–21 nucleotide bases in length.

It acts as a probe in southern blot assay or simpler Dot blot assay to identify the presence of a target.

It is an important research tool in genetic testing, forensics, and Molecular Biology.

The probes can detect a difference of as little as 1 base in the sequence targeted.