Question

Hello question is in the file below please be quick <33

Answer 1

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Step-by-step explanation:

It effected them greatly, the explorers were used to diseases like smallpox, but the native Americans weren't, they didnt have the immunity to fight them so in result they died.

Answer 2

Disease was devastating to the native populations of North and South America. Smallpox ran rampant among the natives as they hadn’t become immune through exposure. Roughly 500,000 natives died from smallpox, and other illnesses.