Cell division is normally controlled by several factors to avoid endless divisions or to avoid the division to continie if there are abnormalities in the DNA or cell's structure.
The insensitivity to ani-growth signals indicates that the cell does not recognize the regulation and continues the cell cicle, i.e. the cells display an uncontrolled cell division. This happens with cancer cells, where the cel cycle is no londer regulated.
The option that best describes this situation is option C. Cancer cells bein able to continue growing forever.