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Use the sample data and confidence level given below to complete parts (a) through (d). A drug is used to help prevent blood clots in certain patients. In clinical trials, among 4519 patients treated with the drug. 133 developed the adverse reaction of nausea Construct a 90% confidence interval for the proportion of adverse reactions. a) Find the best point estimate of the population proportion p.

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User Tribus
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We will have the following:

*First: We determine the standard deviation of the statistic, this is:


\sigma=\sqrt[]{(\sum ^(133)_1(x_i-\mu)^2)/(N)}

So, we will have:


\mu=(\sum^(133)_1x_i)/(N)\Rightarrow\mu=(8911)/(133)\Rightarrow\mu=67

Then:


\sigma=\sqrt[]{(\sum^(133)_1(x_i-67)^2)/(133)}\Rightarrow\sigma=\sqrt[]{(196042)/(133)}\Rightarrow\sigma=\sqrt[]{1474}\Rightarrow\sigma=38.39270764\ldots

And so, we obtain the standar deviation.

*Second: We determine the margin of error:


me=cv\cdot\sigma

Here me represents the margin of error, cv represents the critical value and this is multiplied by the standard deviation. We know that the critica value for a 90% confidence interval is of 1.645, so:


me=1.645\cdot38.39270764\ldots\Rightarrow me=63.15600407\ldots\Rightarrow me\approx63.156

*Third: We determine the confidence interval as follows:


ci=ss\pm me

Here ci is the confidence interval, ss is the saple statistic and me is the margin of error:


ci\approx133\pm63.156\Rightarrow ci\approx(69.844,196.256)

And that is the confidence interval,

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User Davidhu
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