Final answer:
Maryland was the southern colony founded as a safe place for Catholics seeking freedom from religious persecution.
Step-by-step explanation:
The southern colony that was founded as a safe place for Catholics who were being persecuted in England is Maryland. Maryland was founded in 1633 and offered religious freedom to all Christians. The colony's Toleration Act of 1649 guaranteed religious freedom to all Christians but excluded those who denied the divine nature of Christ. The southern colony that was founded as a safe place for Catholics who were being persecuted in England is Maryland . Maryland became an attractive location for Christians seeking freedom from religious persecution.