Final answer:
Michelangelo is well-known for his sculpture of David, the painting of The Last Judgment in the Sistine Chapel, and the Pietà in St. Peter's Basilica, among other works.
Step-by-step explanation:
One of Michelangelo's most famous works is the sculpture of David, completed in 1504. This masterpiece is considered a prime example of High Renaissance sculpture and has become one of the most recognized works in the history of art. Another significant work is the painting of The Last Judgment in the Sistine Chapel, which showcases Michelangelo's masterful use of chiaroscuro and vibrant colors. The chaotic and impactful scene marked a departure from the orderly Medieval depictions of the subject. Michelangelo's creative genius is also evident in his Pietà, located in St. Peter's Basilica, Vatican City, which exudes ideal beauty and grace.