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Which of these drugs is nephrotoxic? A. NSAIDs B. ACE inhibitors C. Diuretics D. Sodium bicarbonate/ Potassium bicarbonate

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Final answer:

The drug among the options provided that is most likely to be nephrotoxic is NSAIDs. However, this doesn't mean that every person who takes NSAIDs is at risk, particularly acute risk. ACE inhibitors, diuretics, and sodium or potassium bicarbonate are often prescribed to manage various kidney conditions.

Step-by-step explanation:

In the context of the question posed, which of these drugs is nephrotoxic, the correct answer is A. NSAIDs. Nephrotoxicity refers to the tendency of certain substances to cause damage to the kidneys. Nonsteroidal anti-inflammatory drugs, or NSAIDs, can potentially cause harm to the kidneys by disrupting the regular blood flow to the organ. This interruption can lead to acute kidney injury, especially in individuals with pre-existing kidney conditions.

By contrast, ACE inhibitors, diuretics, and bicarbonates like sodium and potassium bicarbonate are typically prescribed to manage various kidney conditions. ACE inhibitors help control blood pressure, thus reducing kidney damage in people with hypertension or diabetes. Diuretics, which increase urine output, also aid in controlling high blood pressure. Finally, bicarbonates are used to help manage acidosis, a condition that can occur in chronic kidney disease when the kidneys are unable to adequately remove excess acid from the body.

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