Final answer:
Yes, it's true. The Iroquois Confederacy posed a considerable challenge to the English expansion in Virginia and the Carolinas due to their political, military, and economic strength.
Step-by-step explanation:
The statement is true. The Iroquois League, also known as the Iroquois Confederacy, was indeed a significant obstacle to the English colonial expansion in the regions of Virginia and the Carolinas. The Confederacy was a powerful alliance of five (later six) native American nations - the Mohawk, Oneida, Onondaga, Cayuga, Seneca, and Tuscarora. This union had a profound influence, possessing political, military and economic strength that the English settlers found challenging to overcome.
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