Final answer:
MPF, Cdk, and various enzymes work together to control the cell cycle progression. Cdk binds with Cyclin to form active MPF, which is initially inhibited by phosphorylation but later activated by dephosphorylation. Cyclin degradation leads to a reduction in MPF activity and completion of the cell cycle.
Step-by-step explanation:
The relationship between MPF (Maturation Promoting Factor), Cdk (Cyclin-dependent kinase), and the enzymes that phosphorylate and dephosphorylate MPF and degrade cyclin is crucial in the process of cell division.
MPF is a protein complex formed by Cdk and Cyclin. Cdk is an enzyme that gets activated when it binds with Cyclin. They work together to control the progression of the cell cycle. When Cyclin levels rise, it binds to Cdk, forming the active MPF.
As for phosphorylation and dephosphorylation, some other enzymes phosphorylate Cdk, while there are other enzymes that remove these phosphate groups (dephosphorylate). Initially, the phosphate groups inhibit the activity of MPF. However, the removal of the inhibitory phosphate groups by specific phosphatases leads to the activation of the Cdk, converting the complex into an active MPF, allowing the cell cycle to progress.
At the end of the cell cycle, Cyclin gets degraded by another set of enzymes, causing MPF activity to drop, leading to the cell exiting the mitosis phase and completing the cell cycle.
Learn more about Cell Cycle Regulation