Question

Under conditions when glucose oxidation is elevated, the acetyl-CoA produced will allosterically activate which of the following enzymes leading to an increase in the production of oxaloacetate?

a. Pyruvate carboxylase

b. Citrate lyase

c. Acetyl-CoA carboxylase

d. Malate dehydrogenase

Answer 1

The correct answer is ( a. Pyruvate carboxylase).

When glucose oxidation is elevated, the acetyl-CoA produced will allosterically activate the enzyme pyruvate carboxylase, leading to an increase in oxaloacetate production.