Question

Which of the following is true for the signaling system in an animal cell that lacks the ability to produce GTP? a. It would adapt by switching to G-protein-independent signaling pathways; the cell would respond normally to external stimuli.

b. It would not be able to activate G-proteins. c. It would become hypersensitive to any stimulus that activates GPCRs. d. None of these answers are correct e. It would be forced to use ATP instead of GTP to activate G- proteins, depleting the available ATP in the cell.

Answer 1

An animal cell that cannot produce GTP would not be able to activate G-proteins, leading to a disruption in GTP-dependent signaling pathways.

Step-by-step explanation:

For an animal cell that lacks the ability to produce GTP, the correct answer is that it would not be able to activate G-proteins. G-proteins require GTP to become active, and without it, the signal transduction pathways that involve G-proteins would be disrupted. G-proteins are pivotal in many cellular processes, and their activation is crucial for the proper functioning of a range of physiological responses. In G-protein signaling, once a ligand binds to the receptor, a G-protein binds GTP and then activates other proteins in the cell, such as adenylyl cyclase, starting the signaling cascade. If a cell cannot produce GTP, this means that key signaling pathways and cellular responses would be inhibited, as G-proteins can not use ATP as an alternative to GTP.